I do all my work with 2 Linux machines, one does the blog work, and the other takes care of multimedia. After 2 years of running Debian unstable, I was finally starting to screw it up. All sorts of weird things, especially with the new boot loader - grub. These are things you just can't fix anymore.
So, I bit the bullet, backed up everything to a spare hard disk, and used the latest Debian installer. It worked great! All my custom programs had to be re-compiled, but that was a good thing, as well.